Stem cell assay reveals early development of Rett neurons

Researchers have developed the first stem cell system that makes it possible to study the early development of neurons from people with Rett syndrome, a rare disorder on the autism spectrum.

With the approach, reported 12 November in Cell, the scientists show that stem cells derived from the skin of people with Rett  syndrome generate fewer functional neurons than do those from healthy individuals.

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Image courtesy of Carol Marchetto and Alysson Muotri.

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